Намного? (IPv4)
GRE (Generic Routing Encapsulation) is a tunnelling protocol that was originally developed by Cisco. It can encapsulate a wide variety of protocols creating a virtual point-to-point link.
GRE is the same as IPIP and EoIP which were originally developed as stateless tunnels. Which means that if the remote end of the tunnel goes down, all traffic that was routed over the tunnels will gets blackholed. To solve this problem, RouterOS have added 'keepalive' feature for GRE tunnels.
GRE tunnel adds a 24 byte overhead (4-byte gre header + 20-byte IP header).